Endocrine Abstracts

Background: It is known women suffer from macroprolactinaemia more frequently than men. Often men with unclear genesis of hyperprolactinaemia have normal or a little depressed Testosterone level. High macroprolactin level in blood serum can explain this type of hyperprolactinaemia.Materials and methods: Sixty-four men with hyperprolactinaemia (Prl >600 mU/l) were studied. Clinical, biochemical and MRI methods were used. Prl and Testosterone levels we...

The aim of said presentation was to direct attention to possibility of misdiagnosis of patients with a giant prolactinomas.A 36 years-old man was admitted to our Centre with complaints of headaches, decline of left eye vision, absence of erection, accompanied with a decline in libido and galactorrhea. These symptoms began since August 2001. At October 2004 reduction of the vision on both eyes was revealed as well as contraction of vision fields. At the p...

Recently, the phenomenon of macroprolactinaemia has manifested itself into a great interest for physicians. This problem forces both physicians and patient to waste sizeable resources, and can lead to iatrogenic and unjustified emotional stress and further material losses. At the same time the problem of differential diagnostics of pseudoprolactinomas and true prolactinomas remains challenging. The purpose of the present study was to determine the clinic-analytical repercussio...

This study evaluated the effects of the long treatment with cabergoline on seminal fluid parameters and sexual and gonadal function in hyperprolactinemic males. Eleven males with macroprolactinoma were treated with cabergoline at a dose of 1.5–2.5 mg a week for 6 months. All the patients suffered from libido impairment, reduced sexual potency, six had infertility. In three patients provocative bilateral galactorrhea was found.Seminal fluid analysis,...